REPAIR TABLE for MyISAM tables is similar to using myisamchk for repair operations, and some of the same performance optimizations apply:

Suppose that a myisamchk table-repair operation is done using the following options to set its memory-allocation variables:

--key_buffer_size=128M --sort_buffer_size=256M
--read_buffer_size=64M --write_buffer_size=64M

Some of those myisamchk variables correspond to server system variables:

Each of the server system variables can be set at runtime, and some of them (myisam_sort_buffer_size, read_buffer_size) have a session value in addition to a global value. Setting a session value limits the effect of the change to your current session and does not affect other users. Changing a global-only variable (key_buffer_size, myisam_max_sort_file_size) affects other users as well. For key_buffer_size, you must take into account that the buffer is shared with those users. For example, if you set the myisamchk key_buffer_size variable to 128MB, you could set the corresponding key_buffer_size system variable larger than that (if it is not already set larger), to permit key buffer use by activity in other sessions. However, changing the global key buffer size invalidates the buffer, causing increased disk I/O and slowdown for other sessions. An alternative that avoids this problem is to use a separate key cache, assign to it the indexes from the table to be repaired, and deallocate it when the repair is complete. See Section 7.9.2.2, “Multiple Key Caches”.

Based on the preceding remarks, a REPAIR TABLE operation can be done as follows to use settings similar to the myisamchk command. Here a separate 128MB key buffer is allocated and the file system is assumed to permit a file size of at least 100GB.

SET SESSION myisam_sort_buffer_size = 256*1024*1024;
SET SESSION read_buffer_size = 64*1024*1024;
SET GLOBAL myisam_max_sort_file_size = 100*1024*1024*1024;
SET GLOBAL repair_cache.key_buffer_size = 128*1024*1024;
CACHE INDEX tbl_name IN repair_cache;
LOAD INDEX INTO CACHE tbl_name;
REPAIR TABLE tbl_name ;
SET GLOBAL repair_cache.key_buffer_size = 0;

If you intend to change a global variable but want to do so only for the duration of a REPAIR TABLE operation to minimally affect other users, save its value in a user variable and restore it afterward. For example:

SET @old_myisam_sort_buffer_size = @@global.myisam_max_sort_file_size;
SET GLOBAL myisam_max_sort_file_size = 100*1024*1024*1024;
REPAIR TABLE tbl_name ;
SET GLOBAL myisam_max_sort_file_size = @old_myisam_max_sort_file_size;

The system variables that affect REPAIR TABLE can be set globally at server startup if you want the values to be in effect by default. For example, add these lines to the server my.cnf file:

[mysqld]
myisam_sort_buffer_size=256M
key_buffer_size=1G
myisam_max_sort_file_size=100G

These settings do not include read_buffer_size. Setting read_buffer_size globally to a large value does so for all sessions and can cause performance to suffer due to excessive memory allocation for a server with many simultaneous sessions.